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N-Carbon Quantum Dots for Chromosome Imaging

Hello! My name is Betul Sener and my research project is about finding an alternative way to dye chromosomes that can be used to facilitate genomic research!
Graduation Year
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Project description

In recent years, genetic research has been developing rapidly and taking on a larger role in research and medicine. The synthesis of any particle that can be used in this research can pave the way for new developments in this field. This research aims to develop a chemical method to produce nitrogen-doped carbon quantum dots - economical and bio-sourced substances that bind to genomic DNA. Carbon quantum dots are produced by the green synthesis hydrothermal method from radish, which is abundant in nature, and economically affordable. Nitrogen is added to increase the fluorescence properties of the produced carbon quantum dots and to improve their binding to DNA. The synthesized nitrogen-doped carbon quantum dots (N-CQDs) were tested through chromosome imaging subsequently. It was shown that N-CQDs can bind to the chromosomes, and N-CQDs reflected green light better than DAPI under the FITC filter, a potential advantage of using N-CQDs over DAPI in chromosome imaging.

N-Carbon Quantum Dots for Chromosome Imaging
Project outcome

Produced N-CQDs from radish and imaged its role in bioimaging chromosomes.

PhD Doctor of Philosophy candidate
cell biology, molecular biology, bioengineering, biology
Mentor review

She has helped me through the writing together. She was willing to increase my understanding of an academic writing.

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