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How Histamine Can Treat Circadian Dysfunction

Project by Polygence alum Inika

How Histamine Can Treat Circadian Dysfunction

Project's result

The goal of this project was to create a cohesive research paper that appeals to people of all backgrounds. Through easy-to-understand tables and diagrams explaining complex neuronal mechanisms and brain pathways, this paper proposes novel treatments for common and unique circadian dysfunction through histamine, an allergy-focused neurotransmitter. A STEM Conference Talk was delivered live at Polygence’s 9th Symposium of Rising Scholars

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Inika is pursuing a research project to characterize and communicate the involvement of histamine in the various brain regions. She will write a research paper focused on the interactions of histamine receptors in disease states and how drug interactions might impact them. As part of her research project, she will also produce an infographic that is geared towards patients and the public who might be interested in how anti-histamines might interact with other parts of the brain. There will be focus on primary research papers that highlight the involvement of this widespread system in depression, Parkinson's and other disorders.



Polygence mentor

PhD Doctor of Philosophy candidate


Biology, Chemistry, Neuroscience, Psychology


Neurobiology of sensory systems, modulation by acetylcholine, dopamine, norepinephrine, animal behaviors, human sensory research, pharmacological interactions with sensation




Graduation Year


Project review

“The mentor was great, the resources given were helpful. ”

About my mentor

“He was very knowledgeable in understanding the brain. He knew exactly what I struggled with, and he knew how to help me. ”