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Gene Therapy With CRISPR-Cas9 To Treat Multiple Sclerosis

Project by Polygence alum Emel

Gene Therapy With CRISPR-Cas9 To Treat Multiple Sclerosis

Project's result

This project has been published on Research Archive of Rising Scholars.

They started it from zero. Are you ready to level up with us?


Multiple Sclerosis (MS) is a chronic immune-mediated neurodegenerative disease leading to progressive demyelination and atrophy in the brain. This project aims to first briefly highlight immune mediators of the disease, especially regulatory T cells (Tregs). The project will then discuss biomarkers associated with MS, focusing on those expressed by Tregs. Subsequently, the CRISPR-Cas9 system and how it targets genes for deletion, insertion, or replacement will be described. The final part of the project will discuss different targets and delivery methods for CRISPR-Cas9 therapy for MS.



Polygence mentor

PhD Doctor of Philosophy candidate


Neuroscience, Biology


Neuroscience, Biology, Alzheimer's Disease, Multiple Sclerosis, Cell and Molecular Biology, Immunology




Hello! My name is Emel and I'm a high school graduate. I'm planning to study molecular biology and neuroscience in college to pursue my dream of becoming a scientist one day.

Graduation Year


Project review

“My project expectation was to conduct my own research with my mentor and this expectation of mine was met on Polygence.”

About my mentor

“He was amazing. He helped me a lot and guided me throughout the process. He was so friendly as well.”