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Gene Therapy With CRISPR-Cas9 To Treat Multiple Sclerosis

Emel
Emel
Hello! My name is Emel and I'm a high school graduate. I'm planning to study molecular biology and neuroscience in college to pursue my dream of becoming a scientist one day.
Graduation Year
2022
Student review
My project expectation was to conduct my own research with my mentor and this expectation of mine was met on Polygence.
Project description

Multiple Sclerosis (MS) is a chronic immune-mediated neurodegenerative disease leading to progressive demyelination and atrophy in the brain. This project aims to first briefly highlight immune mediators of the disease, especially regulatory T cells (Tregs). The project will then discuss biomarkers associated with MS, focusing on those expressed by Tregs. Subsequently, the CRISPR-Cas9 system and how it targets genes for deletion, insertion, or replacement will be described. The final part of the project will discuss different targets and delivery methods for CRISPR-Cas9 therapy for MS.

Gene Therapy With CRISPR-Cas9 To Treat Multiple Sclerosis
Project outcome

This project has been published on Research Archive of Rising Scholars.

Read the research paper

Joshua
Joshua
PhD Doctor of Philosophy candidate
Subjects
Neuroscience, Biology
Expertise
Neuroscience, Biology, Alzheimer's Disease, Multiple Sclerosis, Cell and Molecular Biology, Immunology
View Polygence mentor page
Mentor review

He was amazing. He helped me a lot and guided me throughout the process. He was so friendly as well.

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