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Cannabinoids as a Therapeutic Treatment of Alzheimer's Disease

Project by Polygence alum Rohan

Cannabinoids as a Therapeutic Treatment of Alzheimer's Disease

Project's result

My research paper was published in the Curieux Academic Journal and I had the opportunity to present at the Polygence Spring 2023 Symposium.

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Millions of people worldwide suffer from dementia and various forms of neurodegenerative diseases. The most common neurodegenerative disease, as well as the most common cause of dementia, is Alzheimer’s Disease (AD). AD in the brain is physiologically characterized by amyloid beta (Aβ) plaques, hyperphosphorylation and aggregation of Tau, neuroinflammation, and synaptic loss. These processes all result in progressive cognitive decline in neurological functions such as memory, attention and judgment. As there is no cure nor many viable treatment options in which the benefits outweigh potential side effects, the search for possible treatments options continues. One category of treatments that shows promise are cannabinoids, the most notable of which are cannabidiol (CBD) and delta-9-tetrahydrocannabinol (THC). In this review, I will discuss in vivo and in vitro studies showing positive behavioral, neuroprotective, and neuroregenerative impacts as a result of cannabinoid treatment. These properties of cannabinoids exhibited in the treatment of AD show a lot of promise and thus deserve further research and consideration as a potentially effective therapy.



Polygence mentor

PhD Doctor of Philosophy candidate




genetic and molecular controls of plant cellular processes relevant to combat the climate crisis; CRISPR-Cas9 genome mediated engineering in plants; developmental, cell, and molecular plant biology





Mountain View High School

Graduation Year


Project review

“It was a great step into the research world, and I enjoyed being able to to explore a topic that was very interesting to me and a potential solution to a very pressing issue. The work I did at Polygence truly feels like a contribution to the scientific community.”

About my mentor

“My mentor gave me the perfect level of independence and support, letting my explore my topic, review other research papers, and write my review while also giving me guidance regarding scientific writing and the field of plant biology.”