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Browse project ideas by Polygence mentors
What makes your favorite microbe so special?
Get experience understanding how genes and genomes allow certain bacteria to thrive in certain environments and others to struggle. - Develop your own hypothesis on which traits may help your microbe of interest! out compete others. - Learn where to find genomes and how to interpret their gene content using data science methods and (free & user-friendly) publicly available genomics tools! - Compare your microbe's genome to other microbe genomes and determine if your hypothesis is supported by your comparative genomic analysis! All of these things are essential parts of every day life of a researcher. Learning how to conduct this work is invaluable for getting started conducting actual research.
Biology, Biotech, Computer Science
Exploring Active Galactic Nuclei Light Curves
Active galactic nuclei are the powerhouses and central engines of large galaxies across the universe. These central engines are responsible for a multitude of phenomenon. One way to truly understand what is happening and why, is to better understand the variable nature of the light we see coming from these objects. We do this by studying light curves in different wavelengths. By taking these light curves and seeing how they change in brightness over different timescales, we can learn more about whats happening at the centers of these large galaxies and the black holes within them. All data used in this project is publicly available and accessible with the potential of a scientific research paper, presentation or letter as result.
Physics
Inspection Time Reduction Project
Suppose you are supporting a manufacturing operations environment and you have designed a brand new design that is ready for production. There is a critical operation step that requests detailed inspection of the newly designed product. You have been tasked by your supervisor to design an inspection tool that can significantly reduce inspection time per part and standardize inspection methods. How would you go about this? What steps would need to be taken to validate the effectiveness of the inspection tool?
Engineering
A Business Plan For a New Product or Service Idea
For students with an idea for a new product or new service, this project will guide them through the steps in preparing a business plan and a slideshow pitch deck to attract investors and partners.
Business
An Examination of Recent Changes in the Music Industry
This project examines the literature to see how new technologies such as streaming and lower-cost self-producing songs is affecting the music industry.
Business
Increasing Individual, Group, and Organizational Creativity and Innovation
This research project reviews the importance of increasing individual, group, and organizational creativity and innovation. The project reviews the literature to identify specific approaches and techniques to apply to increase creativity and innovation.
Business
The Impacts of US Increased Import Tariffs on International Business
Recently in 2025, the US has announced increased import tariffs on goods from foreign countries. This research project reviews data on actual and forecast impacts on international business and US employment in manufacturing jobs.
Business
The Impacts of AI on Business, Management, and Leadership
Artificial Intelligence (AI) as a new tool has a major impact on business, management, and leadership. This research project reviews the literature on these impacts: both positive and negative. Recommendations are presented for companies considering the adoption of AI.
Business
Introduction to computational analysis of biological images.
One of my areas of expertise is automated biological image analysis. Microscopy imaging is a common and useful tool to readout biological data. Processing and analyzing biological images are important skills for biologists to acquire if they are to become independent researchers. In this project, students will develop basic skills in quantifying biological images using introductory level Python script. Students will be presented with microscopy images and will learn to extract useful information, such as pixel colocalization. Using introductory level Python-based data visualization, students will compile the relevant information into graphs and interpret the information. The outcome of this project will be a set of Python scripts that 1) reads and quantifies biological imaging data and 2) plots the relevant data intuitively. Given enough time, students could compile these scripts into a standalone desktop application.
Nutrition
Fundamentals of stem cell biology
My primary area of expertise is stem cell and tissue regeneration. In this project, students will choose a regenerative adult tissue and write a scientific review about the resident stem cells of that tissue. The goal is for students to understand the fundamental role of stem cells during tissue regeneration and highlight the characteristic features of a specific stem cell population (eg. from muscle, liver, brain). Students will learn the answers to fundamental questions about stem cell biology, such as, “What is a stem cell? What do stem cells do prior to and after injury? How do they respond to injury? How do they form new tissues?” The outcome of this project will be a review article that can be submitted to a high school-level scientific journal.
Nutrition