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Browse project ideas by Polygence mentors
Understanding the Emotional and Social Challenges Faced by Teenagers Supporting a Parent With Cancer: A Qualitative Analysis
This project aims to explore how teenagers experience and cope with having a parent undergoing cancer treatment. While current literature focuses on patients and adult caregivers, the voices of adolescent family members are often overlooked. This project would entail conducting semi-structured interviews and performing qualitative analysis to learn how cancer affects family dynamics, school life, emotional well-being, and social support for teenage cancer caregivers.
Cancer, Psychology, Medicine

Immune Cell Superheroes
What if T cells, B cells, and macrophages were superheroes with special powers? In this project, you’ll learn the basics of the immune system and then turn those ideas into a creative comic, storybook, or animation.
Cancer, Biology

Which Cancer Treatment Wins?
Many cancers have more than one treatment option, like chemotherapy vs. targeted therapy or targeted therapy vs. immunotherapy. In this project, you’ll choose one cancer and compare two different treatment types in terms of how they work, side effects, and outcomes.
Cancer, Biology

Patient-Friendly Guide to Immunotherapy
Lots of patients hear big words like “checkpoint inhibitor” or “CAR T cells” and feel overwhelmed. In this project, you’ll learn the science behind one type of cancer immunotherapy and then create a friendly guide for patients and families.
Cancer, Biology

From Lab Discovery to Patent to Pill Bottle
How does a molecule discovered in a lab eventually become a medicine at the pharmacy? In this project, you’ll pick one drug/therapeutic and trace its journey from scientific discovery, to patents, to clinical trials, to patients. You’ll see how science, law, and business all connect.
Cancer, Biology

Should We Be Allowed to Patent Life? Ethics of Biotech Patents
Can you own a gene? A microbe? A genetically modified plant? In this project, you’ll explore famous court cases and ethical debates around patenting living things. You’ll analyze pro/con arguments and then create your own position statement or policy proposal.
Cancer, Biology

From Idea to IP: Draft a Mock Patent for Your Own Biotech Invention
Have an idea for a new cancer test, microbiome product, or lab gadget? In this project, you’ll design a simple biotech invention and then create a mock patent application for it. We’ll talk about what makes something “patentable” (novel, useful, non-obvious) and translate your idea into basic claims and diagrams.
Cancer, Biology

Dissecting a Biotech Patent: How Scientists Protect Their Ideas
How do scientists legally “claim” an invention so other people can’t copy it? In this project, you’ll pick a real biotech patent (for a cancer drug, diagnostic, or vaccine) and learn how to read it like a scientist–lawyer. We’ll break down the parts of a patent (title, abstract, drawings, claims) and connect each claim to the underlying biology.
Cancer, Biology

How Do LLMs Compare to Classical Machine Learning?
Students explore how different machine learning methods classify text by comparing classical models (TF–IDF + Logistic Regression / Random Forest) with a large language model such as DistilBERT. Using publicly available Amazon review data, the student learns how to clean text, extract features, train models, and compare their performance. They also visualize how models “see” the data using clustering or dimension reduction like PCA or t-SNE.
AI/ML, Statistics

Topological Data Analysis
Did you know data has a "shape" that can be formally analyzed? Instead of just throwing more and more AI at our data issues, we can analyze deeper structures in data using topology. You could help me develop some formal tools and procedures for this type of analysis, and aplly it to your favorite datasets.
Math, Statistics, Physics
