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Browse project ideas by Polygence mentors
Producing a Podcast
There is more than one way to share research. For this project, we will produce a podcast on a topic that piques your intellectual curiosity. We will learn how to craft a compelling story based on original research. The resulting production will reach a wider audience.
Social Science, History, Literature
Critically Examining Social Media
Social media is often something we enjoy as a form of entertainment, but what if we treated it as a scholarly source? For this project, we will approach social media content in a critical and creative manner to shed new light on a broader idea. In doing so, we'll begin to view platforms like Facebook, TikTok, and Instagram in a new light and will gain a stronger grasp on the power of media to shape public perception.
Social Science, History, Literature
Make a 3D Animation and/or Simulation with Houdini!
In this project you will learn the animation/simulation software Houdini. Throughout this project you will work on a few bite-sized animations specifically targeted to learn various aspects of animation. At the end you will make a larger scale animation of your choice that you would be able to put on your portfolio.
Music, Physics, Animation, Game Design
3. Utilizing publicly available data of sports athletes and their biomechanics (throwing velocity, to predict and extrapolate injury rates (Beginner)
Studying baseball metric data that is publicly offered to analyze and predict elbow ligament injury, damage, and rehabilitation time (return to play).
Medicine
2. Statistical Analyses of Sports Injuries, Grading, and Return to Play in Professional Athletes (Intermediate)
Students can analyze data of using a professional team or sport and the players' injuries, severity, and return to play data to show improvements in medical treatment across spans of time (usually comparing decades). The goal of this project is to produce an abstract and presentation at national conferences
Medicine
1. Systematic Review of Quadriceps Strengthening and Gait Stabilization (Advanced)
This project will review current literature published in the database known as PubMed regarding rehabilitation methods in quadriceps muscle strengthening to improve quality of life and improve morbidity and mortality rates in the aging population. My hope is for students to learn the necessary skillsets to be able to ask a clinical question and answer it properly using multifactorial analyses, and publishing the findings in a journal!
Medicine
Designing Games with Musical Storytelling
Imagine playing. a video game where music and art told the whole story. Adventuring through a mysterious path, audio and visual cues are what direct the player onward in their quest and YOU get to design this experience for the player. Your creativity is the limit! I encourage you to use as many of your own music/sound/art assets as you can, but we will find open source solutions to fill in any gaps. We can get started with any level of experience and you'll leave with a video game prototype!
Music, Game Design
CRISPR & Stem Cells: Unlocking the Future of Genetic Medicine
In this project, you’ll write a scientific review paper exploring how CRISPR gene editing is transforming stem cell research. You’ll dive into how scientists use CRISPR tools to modify stem cells for understanding diseases, testing treatments, and even developing regenerative therapies. You'll learn how CRISPR works, what makes stem cells special, and why these technologies together are reshaping the future of medicine. Through this project, you’ll read scientific papers, analyze recent research breakthroughs, and write a review that summarizes key findings in a clear, organized way. Your paper could be submitted to a high school science journal or serve as the foundation for a future research proposal or college application. You’ll gain valuable experience in: -Literature review and scientific writing -Understanding CRISPR-Cas9 systems -Stem cell biology and therapeutic applications -Ethical and societal implications of gene editing
Biotech
Venture Capital for profit and good (Impact Investing)
Can you invest money in a way that achieves high financial return while also delivering high social impact? As part of this project, you will complete research on (1) what makes an investment a good financial opportunity and (2) what would show us that an investment can deliver positive social outcomes in the future, along with the risks that come with this. You will then try to find examples where both trends exist (or not!) at the same time, to understand whether it is possible to invest successfully for both profit and good - also known as impact investing. The outcome of this project can be an example check-list of what an investor should be looking for when making and investment, and risks they should be aware of.
Economics, Philanthropy, Organizational Leadership
Simple, Actionable Policies From Noisy, Uncertain Data
We live in an exciting time with AI revolutionizing the world around us. However, the Achilles heel of mainstream AI is that it's what many call a "black box" meaning that no-one knows exactly why or how it outputs the things that it does. But what most people don't know is that there's another way; a way that is perfectly readable, understandable, an mathematically proven to get the best results: Mathematical Optimization. There are loads of directions you could go with this. But one idea is this: When trying to determine an investment strategy (whether for your self planning for retirement, or entire nations trying to invest in climate-positive technologies) there is a lot of uncertainty. Using mathematical optimization (particularly, a sub-field called "stochastic programming") we can harness that uncertainty to still come up with clear, easily understood policies that guide how to make decisions. In this project, we'd explore how to mathematically formulate those policies, collect and generate data, and perform the analysis required to determine the best policies to adopt.
AI/ML, Math, Engineering
