Meet PolyGPT, our AI-powered Project Idea Generator
Tell PolyGPT your favorite subject and a few hobbies you're passionate about to generate personalized project ideas.
Log in to explore PolyGPTExplore project ideas with the help of PolyGPT
See your personalized project ideas come to life with PolyGPT! Log in to brainstorm ideas.
We know the jump from your interests to a research project idea can be tricky.
That's why we've built tools to help you find the perfect project idea to lay the foundation of a successful project. Simply copy your favorite idea to your clip board, and paste it in the project idea section of the application.
Browse project ideas by Polygence mentors
Understanding immunodeficiencies and how to treat them
We tend to underestimate the importance of our immune system and really only realize it is there when we have a cold or something similar. However, some children are born without an immune system. This makes them very prone to any type of infection, and when they do get sick, it's a potentially life-threatening condition. Over the last decades, we have made much progress treating these patients. We can use stem cell transplants to cure the disease. Sometimes, we can even fix the problem in the patients own stem cells by using a technique called gene editing. This project will allow you to explore the world of immunodeficiences and current and potentially up and coming therapies!
Biology, Cancer
Understanding Your Maybe Fusion Future Through Plasmas Through Light
Explore a potential key to a sustainable future with technologies and how Python can help analyze big data sets to reveal their basic properties, such as temperature and composition. In this project, you might research magnetic reconnection and plasmoids. Also you might write code to process and interpret spectroscopic data, and gain valuable skills in programming and physics. The results could even contribute to a potential scientific publication. Along the way, you’ll discover more about the interaction between light and matter.
Engineering, Computer Science
Analyzing the Effects of Minimum Wage Increases on Local Employment
Description: Study how increases in the minimum wage affect local employment rates, particularly in industries like retail and food services. Skills/Knowledge: Learn how to conduct a difference-in-differences analysis and interpret results using statistical software. Process: Gather data from government labor reports, analyze the employment effects of minimum wage changes in different regions, and control for other economic factors. Outcome: Create a report or research paper that evaluates the potential effects of minimum wage increases on local job markets.
Statistics, Economics
AI engine for knowledge management in large organizations
A mature organization, such as large corporations, insurance companies, research labs, manufacturing companies, etc., typically gathers years of knowledge and information. This project is focused on creating a search engine that uses AI/ML methods such as natural language processing (NLP) and language models to manage and search through this vast amount of data. The student will : Learn about a common industry problem and its various aspects and considerations Learn about basic principles behind Natural Language Processing and Large Language Models and other AI tools Learn to use common AI/ML Python packages and libraries to implement the models Develop programming and coding skills The main outcome of this exercise would be a prototype in form of a working python-based application.
AI/ML
The diary of diseases: a narrative of human disease through case studies and everything we have left to learn
It is likely that you have at some point in your life known someone who has struggled with chronic illness. Perhaps you yourself may have had this experience. These experiences of disease are recorded for scientific investigation through case studies. Case studies provide us as researchers with a unique window into what diseases can do on a fundamental scientific level. In this project you will use case studies to examine a variety of human diseases. You will conduct primary literature review to document and understand the fundamental biological, genetic, and metabolic basis of these diseases in addition to the key diagnostics, treatment options, and prognosis that patients may face. Once you have conducted your research and identified new insights into the research being done and the discoveries being made, you will report your findings biweekly through a public blog. This blog will share the narrative of chronic illness through the stories of patients who experience them while addressing the findings and developments being made at the forefront of science to address these diseases. This blog will be accessible to the general public, giving you the opportunity to share your unique insight with the general public, better informing the public of the state of research surrounding chronic disease in the world around them through the context of patients who are living with these diseases. This project will allow you the opportunity to examine a variety of diseases and the vast span of scientific knowledge in the field of translational medicine. Through this project you will build skills in complex problem solving, literature analysis, critical thinking, scientific communication, project management, and scientific inquiry. Additionally, you will explore the fields of genetics, medicine, biochemistry, physiology, chemistry, and pharmacology. As a researcher with over six years of experience in the field of chemistry and biochemistry as well as a background in english and literary analysis I will guide you as you develop your project exploring the intersectionality of translational medicine and the lived patient experience through the lens of chronic disease.
Biology, Chemistry
What we do not know about ourselves: cryptic metabolism
You may feel like you know all that there is to know about yourself; however, you would be wrong. Everyday unexplained and unknown metabolism occurs within your own body. Have you ever considered that there are trillions of cells living inside you? These cells include bacteria that live in your gut microbiome. On a deeper level, have you considered how this bacteria may be producing unique compounds (called metabolites) each with the potential to have different and unknown outcomes on your health, lifespan, and even neurological function? In this project you will examine the scientific frontier of the human gut microbiome and its intersectionality with human health, aging, and disease states. You will conduct a primary literature search to identify previously unknown compounds that may be created by unique gut bacteria living inside you. You will examine the roles of these compounds and identify the potential for them to unlock never before recognized impacts on the human body through uncharacterized metabolic pathways. You will develop skills in biochemistry, genetics, and microbiology. Upon the completion of this project you will have a strong background in human metabolism, human disease states and therapeutics, and healthy aging and longevity. You will learn how to think critically, how to develop and investigate scientific questions, and ultimately how to communicate your knowledge and skills through a formal written literature review. Each of these skills will serve as fundamental building blocks in the foundations of your scientific education to be built on as you advance your career. As a mentor I can provide you with scientific insight to assist you as you develop this project. I have spent over six years in the field of biochemistry and the gut microbiome developing an expertise in how to best address the most relevant and exciting questions in the field. Through this project will write and publish a formal scientific literature review to share your own exciting findings and unique perspective with other scientists in the field. In this way you will directly contribute to the new and exciting work being conducted within the field, addressing pressing questions and moving the frontier of science forward!
Biology, Chemistry
Emerging biomedical discoveries with commercial potential - biotech
Trying to convince someone that your idea is a good one is a learned skill that can be refined with practice. It is an acquired skillset in both the: (1) written format as well as the (2) verbal format. Research project ideas: (1) Identifying emerging biomedical observations (e.g., AI for drug discovery) that have high potential to benefit humankind, (2) Evaluating the commercial viability of a biomedical discovery or publicly traded biotech company of your choice, and drafting a proposal to commercialize the product (a core work flow for pharmaceutical companies, biotech companies, and biology-focused financial companies).
Cancer, Finance, Biotech
Current Event Podcast
What are you passionate about researching and educating your community about through a podcast? Students should research their interest among their target demographic and location, connect with subject matter experts in the field, and evaluate current efforts around the issue. Deliverables could include: several podcast episodes, a marketing plan, a pitch for a solution surrounding the issue, or a business plan for monetization.
Organizational Leadership
Substance Use Prevention for Teens and Young Adults
How might we bring awareness, prevention and support to teens and young adults currently experiencing substance use disorder? Using the human-centered design thinking process, students will research and ideate solutions for their community. Students should research substance use among their own demographic and location, connect with subject matter experts in the field, and evaluate current efforts around substance use prevention. Deliverables could include: a research proposal for a government office, media and marketing resources for community-action groups, grant writing, or mock-ups of social supports.
Organizational Leadership
Is the World ready for Crypto, who are the winners and who are the losers
US is the strongest economy in the World, though not without its flaws of course. Unfortunately, its banking and financial systems are one of the world's most complicated yet archaic systems. This is due to so many crisis in the past that had led to too many regulations that make the beast move slowly towards change. Today we are hearing words like, AI , Crypto, Quantum and many other fancy/scary words. How does one maneuver and be successful in this sphere, say over the next 5-10-15 years. You never know, your research may land you as a Founder and CEO of your own Startup company !!
Finance
