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Browse project ideas by Polygence mentors
Why Does the Three-Body Problem Defy Prediction?
Although Newton’s laws precisely describe two-body orbits, adding a third mass produces a fascinating blend of stable resonances and sensitive chaos that cannot be solved in closed form. In this project, you will review foundational research and then design and run your own computational simulations to see how varying initial positions lead to periodic, resonant, or wildly unpredictable trajectories. By engaging with professional journal articles and synthesizing your findings into a concise scientific paper, you will gain hands-on experience in reading the literature, experimenting with models and simulations, and communicating results clearly.
Math, Physics
The Impact of Mentorship on College Student Success
Examine how mentorship—formal or informal—affects college students’ academic confidence, engagement, and sense of belonging. Analyze existing research, interview peers with mentors, or survey student participants in mentorship programs to identify common outcomes and themes.
Business, Social Science
Exploring the First-Generation College Student Experience
Explore the experiences of first-generation college students, focusing on themes like belonging, academic support, and identity. Personal stories or interviews could be conducted to better understand the challenges and strengths of this community in higher education.
Business, Social Science
Crossing the Barrier: How HIV enters the central nervous system
This project explores how HIV crosses the blood-brain barrier and causes neuroinflammation. Students will focus on the role of CD14⁺CD16⁺ monocytes in transporting HIV into the brain and contributing to HIV-associated neurocognitive impairment (HIV-NCI). They will review scientific literature to understand the immune signals involved, including key cytokines and chemokines. Students will create a visual diagram to map the steps from infection to brain dysfunction. The final product will be an infographic or short video aimed at educating a general audience.
Cancer, Biology, Psychology
Create a global app in multiple languages to detect deep fakes cyberattacks in real time
Deep fakes attacks are quite common in today's digital world. Its affecting safety of personal ecosystem at all levels including finances, health, infrastructure and lives. A deep fake detection app in real time can help people be more attentive against deep fake attacks
Computer Science, Organizational Leadership
Stellar Architects: Modeling the Life Cycles of Stars
Have you ever wondered about how astronomers study the life cycles of stars? In this project, you will learn how properties of the star (like its size, mass, chemical makeup) affect how a star ages and behaves with time. Using the stellar evolution code on this website (https://docs.mesastar.org/en/latest/#), you have a whole laboratory for creating all kinds of stars that exist in our universe. You will define the initial characteristics of your stars (e.g., mass, chemical makeup) and then use the code to simulate their evolution over millions or billions of years. You can then experiment by creating different stellar models—for example, by varying the initial mass or the chemical makeup—and compare how these changes affect their brightness, temperature, size, and ultimate fate. This involves analyzing the rich data output from the code to plot evolutionary tracks and understand the underlying physics, which you will accomplish using either the Python, R, or Julia programming languages, depending on your background and interest. All of this information and data about how different stellar properties dictate their evolutionary pathways and final states will be synthesized in a research paper. That will be your opportunity to demonstrate your knowledge and develop skills that researchers use to convey their own findings.
Math, Physics
Developing a Quantum Game
In this project, a student will learn about classical game theory, simple quantum mechanics, and how those can be combined into a quantum game theory. Students will explore the mechanics and implications of quantum games, and the skills to both create such a game and analyze the results of it, including on how to develop an optimal strategy. The student would develop either a review of a game, or an original quantum game and simulate playing it, describing in detail the strategy, payouts, and how this information can be used in the greater body of research and potentially in development in quantum algorithms.
Physics
The Link Between Sleep Deprivation and Academic Performance in Teenagers
We will review clinical and public health literature on how lack of sleep affects cognitive performance, attention, mood, and GPA in high school students. Then I will guide you through the process of organizing this information, translating it into a written manuscript, polishing it into a piece worth of being published, and then submitting to local and national conferences.
Surgery, Neuroscience, Medicine
“How Does Brain Structure Change with Age?”
Using the publicly available Human Connectome Project (HCP) Lifespan or OpenNeuro dataset, you will explore how brain regions change with age. We can examine metrics like brain volume, cortical thickness, or white matter integrity across age groups using preprocessed datasets and create concrete conclusions from our analysis.
Surgery, Neuroscience, Medicine
Financial Effects of the COVID-19 Pandemic
The COVID-19 pandemic substantially affected the US economy. Recovery and relief efforts helped support the US economy during and after the pandemic. However, workers in low-wage jobs (disportionately women and people of color) experienced massive layoffs and may not have recovered. The General Social Survey, an annual nationally representative survey conducted by the National Opinion Research Center at the University of Chicago, asked respondents about their financial circumstances in 2022 compared to before the pandemic: "Thinking about the income of your household before the COVID-19 pandemic compared with now, would you say it has increased, decreased or stayed about the same?’. This study would assess the proportion of respondents who reported decreased income, both overall and by population sub-group. This study is very publishable as it focuses on the financial consequences of COVID.
Public Health, Statistics, Medicine
