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Gulam M R

- Research Program Mentor



Biochemistry, Proteins, Enzymes, Cancer, Biotechnology, Drug Discovery etc.

Project ideas

Project ideas are meant to help inspire student thinking about their own project. Students are in the driver seat of their research and are free to use any or none of the ideas shared by their mentors.

Folate pathway enzymes as cancer targets

Brief Introduction about the project: Some of the folate enzymes are expressed in embryonic development and not in adult tissues but showed overexpression in various cancer types including breast cancer, colon cancer and prostate cancer. These enzymes can be potential targets of cancer treatment as they might have low off-target toxicities. Modern day technologies (computational or experimental) provide ample opportunities to screen these targets and design different molecules which can become drugs to treat these diseases and can benefit the patients in clinic. In this project, you will design a research project that can be completed at any place viz-a-viz home/school, gather data, analyze the data and observe how enzymes work in the body and how their function gets affected in the diseases like cancer and present that data as either a scientific poster or talk. You will learn about the scientific process, how to construct appropriate figures for your data, and how to communicate your results in a formal presentation.

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