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Patrick S

- Research Program Mentor

PhD Doctor of Philosophy candidate


Alzheimer's Disease, Parkinson's Disease, Neurodegeneration, Circadian rhythms, neuroinflammation

Project ideas

Project ideas are meant to help inspire student thinking about their own project. Students are in the driver seat of their research and are free to use any or none of the ideas shared by their mentors.

The Amyloid Hypothesis: Sifting through the controversy

For many years, scientists have thought that amyloid beta was the protein responsible for a patient developing Alzheimer's Disease symptoms. This "Amyloid Hypothesis" is now being questioned in light of current clinical data. Recently, drugs have been developed that reduce amyloid beta in patients. Surpsingly, the drugs worked in reducing amyloid beta, but it did not result in the slowing of disease pathology. Does this mean that the amyloid hypothesis is incorrect? Is amyloid beta less important in the progression of disease then what we once thought? This study aims to elucidate the issues with the amyloid hypothesis and to assess where we stand in our understanding of amyloid beta's contribution to disease.

Coding skills

Fairly proficient in R.

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