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Polygence Scholar2021
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Akhil Kalva

Chattahoochee High SchoolClass of 2024Johns Creek, GA



  • "Alzheimer disease in South Asian communities: Roles for genetics and lifestyle practices" with mentor Jared (Working project)

Project Portfolio

Alzheimer disease in South Asian communities: Roles for genetics and lifestyle practices

Started Mar. 4, 2022

Abstract or project description

Alzheimer’s disease (AD) is the most common neurodegenerative disease, but remains poorly understood. Many factors are thought to play a role in the likelihood of developing AD, such as demographics, genetic risk factors, and lifestyle/diet. There is a gap in understanding how genes and lifestyle activities that are more specific to South Asian communities impact the likelihood of a diagnosis of AD. This research study will explore prevalence, genetic basis due to ethnicity or ancestry, and lifestyle/diet can help understand AD risk in persons of South Asian background. This research matters as it compiles the data that is present regarding probable causes of AD with a relation to specific bodily processes and activities that South Asians encounter, which would be beneficial in the context in understanding to what extent demographics, family history, and diet are truly influential when it comes to finding the roots of AD. The methods that will be used include surveying members of the South Asian community, scanning through numerous medical databases, and discussing with Neurology professionals in various settings. Some potential results may include alleles and genes that disproportionately increase AD risk in persons from South Asian communities, or the specific contents in some foods common in South Asian diets that could increase AD risk.