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Polygence Scholar2023
Meha Farrokhi's profile

Meha Farrokhi

Class of 2024North Vancouver, BC

About

Hello! My name is Meha and I am from Vancouver, BC. I am working on a project relating to CRISPR and it's potential to cure cancer, since I am interested in coming up with new solutions and cures for dangerous disease including cancer I decided to apply my knowledge and enthusiasm to this specific research idea. After I finish my project I would like to participate in the Polygence symposium, submit my research to high school research journals and work on writing my book about cancer!!

Project Portfolio

Exploring the role of CRISPR in cell-based cancer immunotherapy

Started Aug. 2, 2023

Portfolio item's cover image

Abstract or project description

Cancer immunotherapy, particularly CAR-T cells, has transformed the landscape of cancer treatment, offering a paradigm shift in prognosis. To enhance the efficacy of cancer treatment, recent scientific endeavors have concentrated on harnessing the potential of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-associated protein 9 (Cas9) technology where they use this technology to cancer treatments and cancer immunotherapy including the engineered CAR-T cell. There have been a lot of advances including correcting genetic mutation, curing genetic disorders, etc. this review paper will cover cancer immunotherapy, CAR-T cell therapy and it's mechanism, successful clinical trials, ongoing clinical trials, the current limitations as well as the future advantages of this technology.