Class of 2024North Vancouver, BC
AboutHello! My name is Meha and I am from Vancouver, BC. I am working on a project relating to CRISPR and it's potential to cure cancer, since I am interested in coming up with new solutions and cures for dangerous disease including cancer I decided to apply my knowledge and enthusiasm to this specific research idea. After I finish my project I would like to participate in the Polygence symposium, submit my research to high school research journals and work on writing my book about cancer!!
- Exploring the role of CRISPR in cell-based cancer immunotherapy with mentor Divya (Nov. 6, 2023)
Exploring the role of CRISPR in cell-based cancer immunotherapy
Started Aug. 2, 2023
Abstract or project description
Cancer immunotherapy, particularly CAR-T cells, has transformed the landscape of cancer treatment, offering a paradigm shift in prognosis. To enhance the efficacy of cancer treatment, recent scientific endeavors have concentrated on harnessing the potential of Clustered Regularly Interspaced Short Palindromic Repeats (CRISPR) and CRISPR-associated protein 9 (Cas9) technology where they use this technology to cancer treatments and cancer immunotherapy including the engineered CAR-T cell. There have been a lot of advances including correcting genetic mutation, curing genetic disorders, etc. this review paper will cover cancer immunotherapy, CAR-T cell therapy and it's mechanism, successful clinical trials, ongoing clinical trials, the current limitations as well as the future advantages of this technology.