Tarun Baskaran

Project Portfolio

Why do neurons of the CNS not regenerate? A focus on glial cells.

Abstract or project description

Neurons in the periphery are highly adept at regenerating after injury, but neurons of the central nervous system fail to regenerate or die following trauma or in neurodegenerative disease. There is evidence that the cells that surround neurons, rather than the neurons themselves, are responsible for this difference. Here, Tarun will provide an overview of the different injury responses of glial cells in the central nervous system vs peripheral nervous system and explain how these differences may explain the inability of CNS neurons to survive trauma.