Tara Gupta Mohan

How do hormonal aberrations play a role in the etiology and diagnosis of PCOS?

Started May 16, 2022

Abstract or project description

Polycystic Ovary Syndrome (PCOS) in which several fluid filled sacs (known as cysts) form in the ovaries. The hypothalamic-pituitary-gonadal (HPG) axis is responsible for regulating hormonal activity in the reproductive system. A dysregulation in this axis can lead to an imbalance of hormones which results in PCOS. Hormones known to be involved in the etiology of PCOS include the Luteinising hormone (LH) and Follicle Stimulating hormone (FSH) , Insulin and Androgen. There are multiple different methods used to diagnose PCOS including blood tests to detect high levels of androgen in the blood and ultrasounds to identify numerous visible follicles in the ovaries. This paper aims to review the hormone mechanisms that result in PCOS and how these abnormalities can be used to create a diagnosis.