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Polygence Scholar2022
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Sarah Chen

University High SchoolClass of 2025Irvine

About

Projects

  • "How are risk factors for Alzheimer's affected by sex differences in the male and female bodies?" with mentor Gokul (Oct. 22, 2022)

Project Portfolio

How are risk factors for Alzheimer's affected by sex differences in the male and female bodies?

Started May 23, 2022

Abstract or project description

This question analyzes the variety of different risk factors researchers have confirmed that are linked to Alzheimer's. Risk factors can be grouped into genetic and nongenetic categories, but sex differences affect many of them. The paper will start with an overview describing what Alzheimer's disease is, how common it is, common symptoms, progression of the disease, and possible underlying causes or mechanisms. The introduction will also include a brief synopsis of each risk factor that the paper will later address. Then, I will go into the genetic risk factors for Alzheimer's including the different genes that have predisposed people to either early-onset or late-onset Alzheimer's. Some of these genes including APP or Tau proteins that can be detrimental to Alzheimer's progression because of the buildup of plaques and neurofibrillary tangles.