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Polygence Scholar2024
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Rayaan Shaik

Class of 2025Long Grove, Illinois

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Projects

  • "Genetic therapeutics to treat Alzheimer's disease and how they compare to current therapies" with mentor Haley (Oct. 3, 2024)

Rayaan's Symposium Presentation

Project Portfolio

Genetic therapeutics to treat Alzheimer's disease and how they compare to current therapies

Started Apr. 29, 2024

Abstract or project description

Alzhiemers disease is a detrimental disorder impacting the brain of our aging population. There is currently no cure to the disease and medications are subpar. Rayaan's review article will focus on the genetic causes of Alzhiemers disease and how these mutations can be targets for genetic therapies. Genetic therapies to be discussed are CRISPR, ASOs, Nuerotropic factors and AAV delivery. The conclusion of the paper will be to compare the current therapies with these genetic therapies. Which therapies are going to make it out of the clinic and have promise over current treatments and which ones have failed in the clinic. Together this will be an impactful review.