Symposium

Of Rising Scholars

Spring 2024

Prisha will be presenting at The Symposium of Rising Scholars on Saturday, March 23rd! To attend the event and see Prisha's presentation.

Go to Polygence Scholars page
Prisha Pachpande's cover illustration
Polygence Scholar2023
Prisha Pachpande's profile

Prisha Pachpande

Class of 2025Troy, Michigan

About

Projects

  • "How can gene editing therapies lead to the diagnosis and treatment of Leber Congenital Amaurosis?" with mentor Rebecca (Working project)

Project Portfolio

How can gene editing therapies lead to the diagnosis and treatment of Leber Congenital Amaurosis?

Started Apr. 14, 2023

Abstract or project description

Leber Congenital Amaurosis (LCA), a genetic condition, is a rare eye disease that affects the retina, causing blindness. The clinical trials for the treatment have so far been unsuccessful, so there is no determined cure. [Mutations in genes (xyz) are known to be causative of LCA]. I will review primary literature on various gene editing therapies and how they are currently being applied. I will then propose how these potential technologies could be utilized in the treatment and care of this disease. Afterwards, I will run through the different pros and cons that these therapies could pose, and which one is most suitable for further action. I propose [strategy abc], would provide the most therapeutic benefit to patients with LCA.