Maya Hutchby
Class of 2029New York, New York
About
Hello! My name is Maya and my project is on the treatments of aneurysmal bone cysts. I chose to work on this project because I have an aneurysmal bone cyst and I want to raise awareness and find the most successful treatment for this disease. After my project is complete, I will submit my paper to be peer-reviewed and hopefully have it published by a journal.Projects
- "Among pediatric and young adult patients with aneurysmal bone cysts, what treatment options are the most successful?" with mentor Margaret (Oct. 7, 2025)
Maya's Symposium Presentation
Project Portfolio
Among pediatric and young adult patients with aneurysmal bone cysts, what treatment options are the most successful?
Started June 30, 2025
Abstract or project description
Aneurysmal bone cysts (ABC) are a benign but locally aggressive lesion that predominantly affects children and young adults. This review synthesizes the available literature to evaluate and compare the efficacy of current treatment options. The systematic review identified effective treatments for ABCs in pediatric and young adult patients by querying PubMed for English-language studies published between 2020 and 2025, focusing on treatment efficacy in humans and extracting relevant data from the remaining 11 articles that met the inclusion criteria. Minimally invasive treatments like doxycycline sclerotherapy and cryoablation are safe, effective, and show high success rates with minimal complications, making them strong options for first-line therapy in ABCs. Curettage with bone grafting remains the most commonly used and reliable surgical method, offering excellent functional outcomes and low complication rates. Denosumab is reserved for inoperable cases due to its effectiveness but carries a high risk of severe hypercalcemia in children, requiring cautious use. This review will present data from existing publications evaluating existing and upcoming options for treatments of ABCs. The review analyzes existing data on treatment success, complication rates, and recurrence rates associated with both procedures. The goal of this paper is to identify the most effective and durable treatment options for ABCs, ultimately improving clinical practice and patient outcomes.