Katelyn Huang

Mechanisms of Pain and Interaction with Stress

Started June 23, 2026

Abstract or project description

The neuromatrix model carries the idea that the production of pain comes from the brain instead of tissue damage or the peripheral nervous system. This model hypothesizes that various parts of the central nervous system, which include the spinal cord, brain stem, thalamus, cortex, and the limbic system, work together to create the sensation of pain. The biopsychosocial model is the final major component in explaining the complex experience of pain. Specifically, it discusses how pain is an experience created by constant interaction between physical, psychological and social factors. The major focus of this model is treating the entire patient, which include biological, psychological, and social aspects, instead of only the areas where pain is present. For instance, studies have shown that depression, anxiety, pain self-efficacy and general mental health all affect overall function and the magnitude of symptoms