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Polygence Scholar2021
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Joshua Sampson

Middleton High SchoolClass of 2022Middleton, Wisconsin



  • "Genetic mutations in humans conferring resistance to pathogens" with mentor Pavithran (Apr. 20, 2022)

Project Portfolio

Genetic mutations in humans conferring resistance to pathogens

Started Apr. 8, 2021

Abstract or project description

This project will study genetic mutations in humans that grant resistance against pathogens. It will describe the characteristics of these genetic traits, which pathogens they grant resistance to, and the mechanism by which these traits provide resistance. It will also discuss the detrimental aspects of these traits, if any, and the potential applications of the genetic resistance mechanisms. Based on these criteria, the following traits will be discussed within the project: sickle cell hemoglobin and malaria resistance, CCR5(delta)32 and HIV resistance, and duffy antigen absence and malaria resistance. This project will be given in the form of a research review paper.