Polygence Scholar2025
Elizabeth Cho
Class of 2029Belmont, MA
About
Projects
- "What are the difficulties with KRAS-targeted therapy in pancreas cancer?" with mentor Michelle (Working project)
Project Portfolio
What are the difficulties with KRAS-targeted therapy in pancreas cancer?
Started Apr. 16, 2025
Abstract or project description
Pancreatic cancer remains one of the hardest cancers to treat despite advances in treatments for it. It has one of the lowest five-year survival rates of all cancers with standard-of-care chemotherapy. This motivates a need for alternative therapies to improve patient outcomes. The most common driver of pancreas cancer is KRAS, which has been difficult to target. In this project we will analyze different targeted therapy treatments available for KRAS-mutated cancers and how resistance can occur. We will determine the most effective targeted therapy available and how we can improve patient outcomes in the future. The project will be shared through a presentation at a symposium.