Ashmit Roy
Class of 2028San Ramon, California
About
Hello my name is Ashmit Roy and my project is a review on genetic and non-genetic factors that impact muscle growth. After I finish my project I would like to have it published in a journal to share my work with the scientific community.Projects
- "An Integrative Review of Genetic and Non-Genetic Factors Influencing Human Skeletal Muscle Hypertrophy" with mentor Laura (May 30, 2025)
Project Portfolio
An Integrative Review of Genetic and Non-Genetic Factors Influencing Human Skeletal Muscle Hypertrophy
Started Oct. 30, 2024
Abstract or project description
Muscle growth is a complex biological process that is limited by both environmental and genetic factors. This review paper explores the integration of genetic and non-genetic factors and how they impact muscle growth and variation among individuals. Both of these influences have the potential to significantly guide muscle growth, causing a widespread contrast in muscle mass within individuals.
Key genes, which are the Androgen Receptor gene, Myostatin gene, IGF-1 gene, and the ACTN3 gene, cause the largest impacts on muscle hypertrophy, leading to a widespread variation in muscle mass within humans. Other genes, including KDM5B, OBSCN, GIGYF1, TTN, RB1CC1, and EIF3J, have been found to increase strength. Crucial non-genetic factors have also been identified to significantly impact muscle hypertrophy and largely contribute to the overall variation in muscle mass among humans. These factors are sleep, hormones, physical training, nutrition, and age. This knowledge allows personalized fitness and nutrition practice to maximize muscle growth potential and find applications in varied fields from sports science to interventions in medicine.