Arielle Tobi | Polygence
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Symposium

Of Rising Scholars

Fall 2025

Arielle will be presenting at The Symposium of Rising Scholars on Saturday, September 27th! To attend the event and see Arielle's presentation.

Go to Polygence Scholars page
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Polygence Scholar2025
Arielle Tobi's profile

Arielle Tobi

Class of 2026Livingston, New Jersey

About

Projects

  • "Navigating Neurodiversity: A deep dive into diagnoses, treatments, and emerging solutions" with mentor Samantha (Aug. 27, 2025)
  • "How are endorphins a natural remedy for anxiety? (Are endorphins sufficient to alleviate anxiety? Under which conditions?)" with mentor Sage (Aug. 16, 2025)

Project Portfolio

Navigating Neurodiversity: A deep dive into diagnoses, treatments, and emerging solutions

Started July 20, 2025

Portfolio item's cover image

Abstract or project description

Discover the fascinating world of neurodiversity! You'll explore conditions like Autism, ADHD, and OCD to uncover their science, causes, and how they’re represented in media. Dive into real-world topics, learn myths vs. facts, treatment options, and how neurodiverse individuals navigate a neurotypical world. By the end, you’ll gain a deeper understanding of how we can build a more inclusive future in schools, workplaces, and beyond.

Project Portfolio

How are endorphins a natural remedy for anxiety? (Are endorphins sufficient to alleviate anxiety? Under which conditions?)

Started June 9, 2025

Abstract or project description

Generalized anxiety disorder (GAD) causes fear or anxiety responses to innocuous stimuli, exaggerated responses to concerning stimuli, affects over 300 million people globally, and is nearly twice as common in women as in men. This review discusses the underlying neurological changes, as well as the interactions between the brain,body, and sex in this complex disorder. The effects of not only societal expectations, but sex hormones, hormonal cycles, and environmental impacts are discussed. One intervention for anxiety with increasing evidence for its effectiveness is exercise, and specifically its impact on endorphins. Endorphins are opioid neuropeptides released when the body experiences stress or pain and act as the body’s natural pain relievers. Endorphins are also released during exercise. Endorphins modulate stress-related brain activity by binding to mu-opioid receptors, thereby decreasing heart rate and restlessness. Gender also must be considered when evaluating anxiety disorders due to gendered societal expectations and differences in levels of testosterone and estrogen which affect endorphin production. While males and females have similar baseline endorphin levels, the hormonal fluctuations of the menstrual cycle affect endorphins, meaning that sex differences can impact anxiety.. By including multifactorial considerations in GAD, we continue to progress in understanding and improve treatment options and outcomes.