Anna Broderdorf | Polygence
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Fall 2025

Anna will be presenting at The Symposium of Rising Scholars on Saturday, September 27th! To attend the event and see Anna's presentation.

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Anna Broderdorf

Class of 2027

About

Projects

  • "Investigating the Causative Relationship Between Hyperinsulinemia and Pancreatic Cancer" with mentor Natalie (Working project)

Project Portfolio

Investigating the Causative Relationship Between Hyperinsulinemia and Pancreatic Cancer

Started Mar. 11, 2025

Abstract or project description

In this paper I want to discuss a newly found independent risk factor for pancreatic cancer called hyperinsulinemia, or excess amounts of insulin being present in the body. My paper will take a causative approach, stating that hyperinsulinemia plays a key role in pancreatic cancer development. I will first go into detail on the origins of insulin, how it is produced, and then reference simple pancreatic anatomy. Once I have written descriptions for these factors, I will discuss all the data points which support the claim of hyperinsulinemia acting as a factor in pancreatic cancer cell development. These points will fall under general categories of pancreatitis, obesity, inflammation of the pancreas, and the overactivation of pancreatic digestive enzymes. I will include limitations as well to provide more nuance and details to my claims.