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Polygence Scholar2023
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Aditya Gowda Yogananda

Class of 2025Fremont, CA



  • "Stem Cell Therapies on Patients Suffering Ischemic Stroke" with mentor Jen (Oct. 26, 2023)

Project Portfolio

Stem Cell Therapies on Patients Suffering Ischemic Stroke

Started June 3, 2023

Abstract or project description

Ischemic stroke occurs when a blood clot blocks blood flow to the brain. This type of stroke is responsible for causing long term disability and death. Stem cell based treatments have shown the potential to restore lost brain functions and fasten recovery. Various types of stem cells, such as mesenchymal stem cells and induced pluripotent stem cells have demonstrated benefits through different pathways like synaptogenesis (formation of new synaptic connections), angiogenesis (formation of new blood vessels), and neurogenesis (generation of new neurons)1. These therapies have been shown to contribute towards restoring brain tissue and improving outcomes. In addition, this paper discusses the challenges, safety, and limitations that need to be addressed in order to advance stem cell-based therapies for stroke treatment. These include improving targeted delivery of injected cells towards affected areas, determining the most effective route for administering these cells, and understanding early engraftment and distribution patterns post injection2. Ongoing advancements in stem cell research may pave the way for trials and innovative treatment approaches for individuals affected by stroke.