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Polygence Scholar2026
Aalya Arora's profile

Aalya Arora

Class of 2027Dublin, California

About

Hello! My name is Aalya Arora. A bit about me is that I am a martial artist, policy debater, and aspiring neuroscientist. My project explores potential synergies between nanotechnology and stem cell therapies as a target for Alzheimer's disease. After my project is complete, I would like to share my research at forums, as well as foster effective discussion regarding how divergency is bred through today's apotheosized practices and how we can enter an era of scientific mental wellness.

Projects

  • "Nanocarrier–Stem Cell Synergy in Alzheimer’s Disease: Overcoming the Blood–Brain Barrier Through Precision Nanomedicine" with mentor Jessica (Mar. 28, 2026)

Project Portfolio

Nanocarrier–Stem Cell Synergy in Alzheimer’s Disease: Overcoming the Blood–Brain Barrier Through Precision Nanomedicine

Started Aug. 13, 2025

Abstract or project description

Alzheimer’s disease remains a leading cause of dementia worldwide, with no widely effective disease-modifying therapies despite decades of research. A central limitation in therapeutic development is the restrictive nature of the Blood–Brain Barrier (BBB), which prevents the efficient delivery of biologics, including stem-cell-based interventions. Recent advances in nanotechnology and regenerative medicine suggest that combining engineered nanocarriers with stem cell therapies may overcome these translational barriers. This review argues that a combinatorial nanocarrier–stem cell approach produces synergistic improvements in BBB penetration, cellular survival, targeted trophic delivery, and real-time tracking, representing the most promising near-term pathway for disease-modifying Alzheimer’s therapies. Supporting evidence is drawn from mechanistic BBB studies, nanocarrier delivery research, stem cell clinical trials, and emerging work in exosome-mediated transport and theranostics.