Maria B
- Research Program Mentor
MD/PhD Doctor of Medicine and of Philosophy candidate
Expertise
Chemical Biology, Drug Development, Biological Experimental Assay Development
Project ideas
Project ideas are meant to help inspire student thinking about their own project. Students are in the driver seat of their research and are free to use any or none of the ideas shared by their mentors.
Literature Review: 5-HT2 (Serotonin)-specific Small Molecules and Their Potential Applications
5-HT2 receptors (release serotonin) are important for regulation of sleep and play a role in the disease progression of depression. SSRIs target the serotonin transporter (SERT) and are often used for treatment of depression and some sleep conditions. However, specifically targeting serotonin receptor release could provide potential nuance and benefit in treatment of serotonin-related conditions. This review would entail reading about the function of 5-HT2 receptors and explore current research in selective small molecule development.