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Thaddeus W

- Research Program Mentor

PhD Doctor of Philosophy candidate

Expertise

Neuroscience, neurodegeneration, circadian rhythms, neuroimmunology

Project ideas

Project ideas are meant to help inspire student thinking about their own project. Students are in the driver seat of their research and are free to use any or none of the ideas shared by their mentors.

The causes of sleep disruptions in neurodegeneration

Sleep disruptions are a symptom of many different neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. Why do these very different diseases all share this one symptom? Is there one common cause of sleep disruptions in neurodegeneration or do different diseases arrive at this symptom via different pathways?

How does the brain's immune system respond to Alzheimer's disease?

Microglia, the resident immune cells of the brain, change dramatically in Alzheimer's disease. Is this a helpful response or a destructive one? Recent research has provided evidence for both sides. How might this cell type both protect against and exacerbate the progression of Alzheimer's disease?

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