
Thaddeus W
- Research Program Mentor
PhD Doctor of Philosophy candidate
Expertise
Neuroscience, neurodegeneration, circadian rhythms, neuroimmunology
Project ideas
The causes of sleep disruptions in neurodegeneration
Sleep disruptions are a symptom of many different neurodegenerative diseases, including Alzheimer's disease, Parkinson's disease, and Huntington's disease. Why do these very different diseases all share this one symptom? Is there one common cause of sleep disruptions in neurodegeneration or do different diseases arrive at this symptom via different pathways?
How does the brain's immune system respond to Alzheimer's disease?
Microglia, the resident immune cells of the brain, change dramatically in Alzheimer's disease. Is this a helpful response or a destructive one? Recent research has provided evidence for both sides. How might this cell type both protect against and exacerbate the progression of Alzheimer's disease?