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Grace H

- Research Program Mentor

PhD at Duke University

Expertise

Biochemistry, biology, cancer research, animal science, microbiology

Bio

I a Biochemist in the laboratory of Dr. Richard Brennan, Chair of the Department of Biochemistry at Duke University. As an undergraduate student at New Mexico State University, I proactively sought opportunities to engage in scientific research and was able to spend summers as an intern in labs at the Fred Hutchinson Cancer Research Center (as an HHMI scholar) and at Yale University (as a research intern). These opportunities catalyzed my commitment to pursue an advanced academic career in bioscience. Outside of the lab, my biggest hobby is my English setter puppy! I also love gardening, reading, drawing, and watching vintage films.

Project ideas

Project ideas are meant to help inspire student thinking about their own project. Students are in the driver seat of their research and are free to use any or none of the ideas shared by their mentors.

Structural Analysis of Protein Function

My current field of training is in protein structure through X-ray crystallography. Peptide chains fold into secondary, tertiary and quaternary structures that form three dimensional protein structures. Understanding these protein structures helps elucidate function of proteins and why some mutations can cause disease. I can work with a student with a protein of interest (for example, one commonly mutated in a disease of interest) to help them learn prediction software to look at the structure. They can perform a literature search on mutations in this protein and represent these mutations visually and summarize how these mutations abrogate protein function.

Coding skills

N/A

Teaching experience

Duke University School of Medicine Durham, NC Teaching Assistant for Biochemistry 696 Spring 2023 • Lead class journal discussion groups • Teach hands-on Protein Crystallization workshop Duke University School of Medicine Durham, NC Teaching Assistant for Biochemistry 301 Summer 2020 • Facilitated student group projects and held weekly office hours • Grade homework and exams Duke University School of Medicine Durham, NC Doctoral Student in Dr. Richard Brennan’s Laboratory March 2020-Present • Mentor undergraduate student in biophysical methods in the laboratory • Co-mentored National Science Undergraduate Research Project (NSURP) student

Credentials

Work experience

New Mexico State University (2014 - 2018)
Student researcher and HHMI Research Scholar
Yale University (2017 - 2018)
Research Intern and Postgraduate Associate
Duke University School of Medicine (2019 - Current)
Graduate Student
Duke University (2022 - Current)
Duke Scholar in Molecular Medicine

Education

New Mexico State University
BS Bachelor of Science (2018)
Biology, minor in Biochemistry
Duke University
PhD Doctor of Philosophy
Biochemistry, microbiology, pathogenesis, multidrug resistance

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