PhD Doctor of Philosophy candidate
How do genes affect severity of COVID-19?
There is lots of public sequencing data from COVID-19 patients. In this project, you could look at differences in clinical outcomes between patients (i.e. mild cases vs. severe cases) and see which genes are differentially expressed between the cohorts to identify potential predictors of covid response.
Why is Single Cell RNA (scRNA) sequencing so important?
scRNA sequencing lets you explore cellular interactions and evolutions like never before. All of our cells have the same DNA, from our hair cells to our neurons. What differentiates our cells are the genes that get expressed (and in turn, what proteins are being created by each cell). In order to create proteins, cells turn parts of our DNA into RNA. By looking at RNA in each cell, we can determine what genes each cells is expressing to better understand what cells are present and how they are interacting!