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Morteza S

- Research Program Mentor

PhD at Massachusetts Institute of Technology (MIT)

Expertise

Healthcare, Biotech and bioengineering, writing papers (any type), Engineering (especially Mechanical & Biomedical), Medical Device, Physics, Data Science, Programming, Code writing, Machine Learning, Image Processing, Mathematics, App Development

Bio

Can we leverage AI, Robotics, and Engineering tools to make life easier for more than 95% of the world population who are living unhealthy lives? My passion centers on this goal by leveraging technology toward solving major scientific problems. I finished my PhD in Mechanical Engineering at MIT with a focus on developing AI-optimized devices that can make treatment of diseases easier and more accessible to the patients. Previously, I did my Masters and Bachelors degrees both in Mechanical Engineering. I have published ~ 40 scientific publications in competitive journals and conferences, cited +1100 times as of May 2026, in addition to one licensed US patent. I earned a graduate certificate in Business Analytics and another in Healthcare from MIT Sloan School of Management with a focus on AI/ML application in healthcare, as well as a graduate certificate in Medicine from Harvard-MIT Division of Health Sciences and Technology. I am currently a Senior Research Scientist at Gilead Sciences, a multinational pharmaceutical company in the California Bay Area. Prior to that, I was a research scientist at a biotech company, SiO2 Medical Products, an advanced Materials Science company, and prior to that in Syntis Bio, a biotech startup committed to revolutionizing drug delivery systems. I joined here in August 2022, and have ever since mentored +50 research projects, led over 12 Pods centered on AI, provided career advice to +50 high school students, provided publication support to +50 students, and regularly worked as judge/reviewer for the symposium. At least over 11 students expressed after working with me that their experience "exceeded their expectations". I have had students who ranked in the top three in science fair and competitions. My students have successfully published their research studies in top research journals and accepted to ultra competitive colleges such as Stanford University. During my free time, I enjoy biking, outdoor activities such as hiking, walking, and kayaking.

Project ideas

Project ideas are meant to help inspire student thinking about their own project. Students are in the driver seat of their research and are free to use any or none of the ideas shared by their mentors.

A Multimodal AI System for Early Dementia Classification Combining Brain Imaging, Medical Records, and Genetics

Diagnosing dementia early is one of the hardest challenges in neurology — no single test tells the full story. Clinicians must piece together information from brain scans, patient history, lab results, and increasingly, genetic data. In this project, we will build a multimodal predictive model that learns from all of these data sources together, rather than in isolation, to classify dementia risk at an early stage. We will work with paired patient datasets containing MRI scans, electronic medical records, and genetic information, learning how to align and fuse different data types into a single AI pipeline. Along the way, we will grapple with real research challenges — missing data, small sample sizes, model interpretability, and the ethical handling of sensitive patient information. Final deliverable: A trained and evaluated multimodal classification model, along with a research paper reporting model performance, key predictive features across data modalities, limitations, and recommendations for clinical translation.

Developing machine learning models for automated classification of healthy and cancerous tissues based on MRI images

The goals of this project is to develop a Python script for machine learning and write a research paper aimed at developing machine learning models for classification of MRI images. We will go over the following points: 1- Learn how to perform data analysis, image preprocessing, visualization, correlation study, data mining and exploration in Python. How to find high quality datasets online. 2- Learn how to develop and train machine learning algorithms in Python that can identify unhealthy individuals or people with high risk of cancer by looking at their MRI images. How to optimize and compare the performance of these models. 3- Write the results of findings as a research paper to be published in reputable research journals, also showcase your work on public sites such as GitHub and Kaggle. Many of such projects also were proceeded to science fairs. Image Reference: https://www.healthtravellersworldwide.com/cancer-detection-techniques/

Development of a machine-learning guided assistive device for helping disabled people

The goal of this project is to develop a prototype device using 3D printing, microcontrollers and robotics which can be presented in a science fair and published as a research paper. Throughout the project we will cover three skillsets: 1- Prototyping robotic devices with healthcare applications, using 3D printing (optional) 2 -Programming the device using Python to interact the the environment and process the inputs received from the user 3- Test the prototype and evaluate its performance to report findings as a science fair application and/or scientific paper Reference for the image: https://www.selectmedical.com/why-choose-us/advanced-robotics-and-rehabilitation-technology/

Machine learning modeling and app development for early prediction of dementia based on patient's medical records

In this project, we aim to use machine learning algorithms to predict the factors that can contribute to dementia, one of the most serious mental diseases, by analyzing the patient's medical records and history. Through this project, we will go over programming and data analysis in Python, focused on machine learning models. We look into best ways to do research and find datasets online. We will also aim to develop an online app using Python libraries such as Streamlit and Flask to run the trained machine learning models online. Finally, we'll write a research paper to summarize the findings for submission to a research journal.

Smart Health App Development: Integrating Machine Learning for Personalized Healthcare

For our research project at the intersection of app development, healthcare, and machine learning, we will design and prototype a mobile application that leverages machine learning to analyze user-inputted health data and provide personalized health insights. We will use Python as our primary programming language, utilizing libraries such as Pandas and NumPy for data manipulation and numerical analysis, Scikit-learn for building and evaluating machine learning models, and TensorFlow or Keras for deep learning tasks. For data visualization and presenting trends to users, we will incorporate Matplotlib and Seaborn. To develop the app’s backend and APIs, we will consider frameworks like Flask or Django, which are well-suited for healthcare applications due to their scalability, security features, and ease of integration with machine learning workflows. By combining these tools, we aim to create an accessible and intelligent digital health solution that empowers individuals to monitor and manage their health more effectively. Result of this project can also be presented to a Science Fair, Competition or as a research article.

A Multimodal AI System for Tracking ALS Disease Progression Turning Heterogeneous Patient Data into Actionable Clinical Insights

ALS progresses differently in every patient, making it extraordinarily difficult to predict how the disease will evolve and when to adjust care. In this project, we will build a multimodal AI system that integrates data from multiple sources — clinical assessments, speech recordings, wearable sensor data, and electronic health records — to model and predict individual ALS disease trajectories over time. We will work through the real challenges of longitudinal patient data, including irregular measurement intervals, missing data, and the need for models that clinicians can actually interpret and trust. Final deliverable: A multimodal disease progression model evaluated on longitudinal ALS patient data, along with a research paper reporting predictive accuracy, clinically meaningful insights, model interpretability, and recommendations for integration into palliative and supportive care planning.

Generative AI for Synthetic Patient Data in Parkinson's Disease Research Solving the Data Scarcity Problem in Rare Neurological Conditions

One of the biggest barriers to AI research in neurodegenerative diseases is the lack of large, diverse, and well-annotated patient datasets. In this project, we will investigate how generative AI models can be used to synthesize realistic patient data — including motor assessments, clinical notes, and imaging features — for Parkinson's disease research. We will design and evaluate a generative pipeline, rigorously test whether synthetic data can augment real datasets to improve downstream model performance, and critically examine the risks of training clinical AI systems on data that was itself AI-generated. Final deliverable: A generative data pipeline producing synthetic Parkinson's patient data, validated against real-world distributions, along with a research paper evaluating data quality, downstream model impact, and the ethical boundaries of synthetic data use in clinical AI.

LLM-Assisted Early Detection of Cognitive Decline Through Speech and Language Analysis Listening for What the Brain is Trying to Tell Us

Changes in the way people speak and write are among the earliest detectable signs of cognitive decline — yet these subtle shifts are easy to miss in a standard clinical visit. In this project, we will build an AI pipeline that analyzes speech patterns, word choice, sentence complexity, and fluency from recorded patient conversations to flag early signs of cognitive decline associated with Alzheimer's and related dementias. We will explore how LLMs can be combined with audio processing tools to extract meaningful linguistic features, and evaluate the system's ability to distinguish between healthy aging and early-stage neurodegeneration across diverse patient populations. Final deliverable: A multimodal speech and language analysis tool evaluated on clinical or publicly available datasets, along with a research paper reporting predictive performance, key linguistic biomarkers identified, and implications for scalable, non-invasive cognitive screening.

Reinforcement Learning-Based Autonomous Navigation for a Raspberry Pi Robot Building a Low-Cost, Real-World Autonomous Driving Platform

Autonomous navigation is one of the most exciting and demanding challenges in robotics — requiring a system to perceive its environment, make decisions in real time, and recover gracefully from mistakes. In this project, we will design and build a small-scale autonomous driving robot on a Raspberry Pi platform, using reinforcement learning to teach the robot to navigate real-world environments without explicit programming. Starting from scratch, we will assemble the hardware, set up the sensing pipeline using onboard cameras and sensors, and train an RL agent that learns through trial and error to follow lanes, avoid obstacles, and make navigation decisions on the fly. A key focus of this project is bridging the gap between simulation-based training and real-world deployment — one of the hardest open problems in autonomous systems research. Final deliverable: A fully functional Raspberry Pi-based autonomous robot trained using reinforcement learning and tested in a real physical environment, along with a research paper documenting the hardware setup, RL training methodology, sim-to-real transfer strategies, performance results, and lessons learned for scaling to more complex autonomous systems.

Coding skills

Python, MATLAB, R, JMP

Languages I know

Persian

Teaching experience

I have extensive experience at mentoring students (high school level up to graduate level students) through short-term and long-term (mostly) research projects. I joined this mentoring organization in August 2022, and have ever since mentored over 15 research projects, led 2 classroom centered pods, provided career advice to +50 high school students, provided publication support to +20 students, and regularly worked as judge/reviewer for their symposium. My students have successfully published their research in top high school journals such as JSR. Prior to this organization, I have had the pleasure of mentoring more than 10 students in various steps of their careers, resulting in admittance to top schools or high-quality publications.During my master's study (2015-2017), I trained and mentored 4 graduate students and 2 undergraduates on wet lab skills. Some of the skillsets taught include writing manuscripts, running lab experiments, sampling liquid, basic safety considerations, measuring materials quantity (e. g. weight, mechanical properties, chemical properties, etc.). I further helped the graduates students to explore ideas and come up with a topic for their Master's Thesis. These students then proceeded to become top engineers or get admitted to top schools for graduate school in the US or Canada, namely Georgia Tech, McMaster University, University of Arizona, The University of British Columbia, etc. This mentorship also helped graduate mentees publish their results in notable journals including Nature Scientific Report, Materials Science & Engineering- PartC, etc.During my PhD/Post Doctoral studies at MIT (2017-2022), I have had the opportunity to mentor and train a total number of 6 undergraduates (mostly freshmen) from MIT (5/6) or Wellesley College (1/6). We have such strong connection and collaboration that, on average, each student stayed involved in a project for 1.5-2 years. Furthermore, I worked with 3 of these students for more than 2 years and currently working with two of them on an ongoing research project which started back in January 2019. We worked on a broad range of topics ranging from machine learning, programming, wet lab work, microfabrication, device fabrication, polymer chemistry, animal work, cancer research, data analysis, manuscript writing and review, etc. We managed to keep working on these projects even in view of COVID pandemic and its devastating effects on research resources. Results of these collaboration has led to two journal articles in top notch journal Science Advances (one in 2020 and another 2022) as well as two peer-reviewed conference papers. In fact, 5 out of 6 undergraduate mentees enjoyed authorship in these two articles, such that one undergraduate was named second author and the other two named co-third author.In summary, it has always been my utmost pleasure to work with students in any level of their career. I consider mentoring to be a two-sided learning experience and something that needs to be taken more seriously.

Credentials

Work experience

SiO2 Materials Science (2021 - Current)
Staff Scientist (R & D)
MIT (2021 - Current)
Post-doctoral researcher
Kheili Sabz Publication group, Tenran, Iran (2013 - 2017)
Author, scientific examiner & editor
Syntis Bio (Biotech startup) (2023 - 2023)
Scientist

Education

Iran University of Science and Technology Tehran
BS Bachelor of Science (2014)
Automotive Engineering
Sharif University of Technology
MS Master of Science (2017)
Mechanical Engineering (Bio-Nano technology and Design)
Massachusetts Institute of Technology (MIT)
PhD Doctor of Philosophy (2021)
Mechanical Engineering

Completed Projects

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