Kelsey F
- Research Program Mentor

PhD Doctor of Philosophy candidate

Expertise

Genetics/genomics, biochemistry, bioinformatics

Project ideas

Project ideas are meant to help inspire student thinking about their own project. Students are in the driver seat of their research and are free to use any or none of the ideas shared by their mentors.

How do epigenetic marks vary between alleles in individuals?

Each of our cells contain a complete copy of our genome which is made up of over 3 billion bases (A,T,G,C). Our genome is tightly regulated to organize, maintain, and easily access all of that information. One mechanism of genome regulation is through epigenetic marks that affect chromatin structure - how tightly or loosely packed the DNA is. This can vary across individuals and within one individual between the two different copies of each chromosome (one from mom & one from dad). Analyze long read DNA sequencing data to gain insight in how certain epigenetic marks can vary between alleles for the same gene in one individual. (image from https://www.mechanobio.info/genome-regulation/what-is-chromatin-heterochromatin-and-euchromatin/)

Coding skills

python, bash, some R,

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