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Daniel

PhD Doctor of Philosophy candidate

Expertise
Biology, microbiology, biochemistry, cellular and molecular biology, genetics, physical biology

Project ideas

Project ideas are meant to help inspire student thinking about their own project. Students are in the driver seat of their research and are free to use any or none of the ideas shared by their mentors.

Size determination- Can we find patterns using genetics comparing synthesis enzymes?

Even in one shape set of organisms, say rod-shaped, there is a variety of widths that these organisms can have. Further, we know these organisms use peptidoglycan in their cell walls as the structural component, and although there are large similarities in the class of proteins that build the cell wall, there is still a large discrepancy for how this size variation arises. Can we go through all possible rod-shaped organisms, find there average diameter, and compare genetic sequences of their cell wall synthesis enzymes?

Outlining shapes of cells- Segmentation

One of the very first steps and problems in quantifying data from imaging is to draw an accurate outline around the cell- which we call segmentation. In this project, we will use and compare existing software to segment images of bacteria. The goal is to learn how these programs work, as well as optimize systems to segment a variety of shapes of cells.

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